PATHOPHYSIOLOGY OF BLEEDING DIATHESIS IN HAEMOPHILIA-A: A SEQUENTIAL AND CRITICAL APPRAISAL OF NON-FVIII RELATED HAEMOSTATIC DYSFUNCTIONS AND THEIR THERAPEUTIC IMPLICATIONS

Haemophilia-A is characterized by deficiency of FVIII, but the bleeding diathesis is not a mere reflection low FVIII activity.The pathophysiology of haemophilic bleeding diathesis is a complex interplay between defective procoagulant function and up-regulated fibrinolysis.Moreover, haemophilic bleeding diathesis is frequently compounded by treatmen

This christams paper solves the problem of optimal placement of shunt capacitors in the northern region of Bangladesh transmission network.During network augmentation event like very high inductive reactive load condition, the weakened voltage profile of the buses can be compensated by optimum allocation of the capacitor banks.In this regard, the a

In this paper, we consider the mechanical effect of the sulfate attack on concrete.The durability analysis of concrete structures in contact to external sulfate solutions requires the definition of a proper diffusion-reaction model, for the computation of the varying sulfate concentration and of Socks the consequent ettringite formation, coupled to

The vagina contains at least a billion microbial cells, dominated by lactobacilli.Here we perform metagenomic shotgun sequencing on cervical and fecal samples from a cohort of 516 Chinese women of reproductive age, as well as cervical, fecal, and salivary samples from a second cohort of 632 women.Factors such as pregnancy history, delivery history,

Abstract As a key component of electron multiplier device, a microchannel plate (MCP) can be applied in many scientific fields.Pure aluminum oxide (Al2O3) as secondary electron emission (SEE) layer were deposited in the pores of MCP via atomic layer deposition (ALD) to overcome problems such as high dark current Strength conditioner and low lifetim